Antioxidant and Free Radical Scavenging Activity in Roots of Hygrophila schulli (Buch.-Ham.) M.R.Almeida & S.M. Almeida

Murugan S¹ , Kumar GV²

Section:Research Paper, Product Type: Isroset-Journal
Vol.5 , Issue.4 , pp.12-16, Aug-2018

CrossRef-DOI:   https://doi.org/10.26438/ijsrbs/v5i4.1216

Online published on Aug 31, 2018

Copyright © Murugan S , Kumar GV . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 

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Abstract :
Nowadays herbal medicines form an important part of health care system, due to lots of side effects and complications in the modern medicine. The novel compounds synthesized in plants as secondary metabolites are the potential source of therapeutical uses. Plants produced significant amount of novel compounds to prevent the oxidative stress related diseases and can be used as antioxidant. One such attempt had been made in the present study in investigating the roots of Hygrophila schulli member of acanthaceae family for an antioxidant activity. The roots of H.schulli were extracted using petroleum ether as a solvent. Various assays such as DPPH (1,1-diphenyl 2-picryihydrazyl) free radical, ABTS radical cation, Phosphomolybdeunm reduction assay and ferric reducing power activity were checked for the antioxidant ability and free radical scavenging activity. In all these assays the root extract of H.schulli showed maximum reducing activity of free radical scavenging activity. The IC 50 value of the root extract in each assay was compared with the standard value of ascorbic acid and found Hygrophila schulli has a strong antioxidant and free Radical Scavenging Activity.

Key-Words / Index Term :
Hygrophila schulli, antioxidant, Free radical, DPPH, ABTS, Phosphomolybdeunm, Fe3+

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